Rabies infection in Kidney : A hope for treatment in the future

Document Type : Mini review


Queen Saovabha Memorial Institute, The Thai Red Cross Society 1871 Rama 4 Road, Pathumwan Bangkok


< p>Rabies is a serious zoonotic disease. Which currently no treatment method to cure and most of the infected patients die. The rabies virus invades the peripheral and central nervous system (brain), resulting in encephalitis and organ failure. But besides the nervous system, Rabies virus can also be found in other various organs such as kidneys, valves, intestines, heart, intestines, corneas, etc., with evidence through organ transplantation. The organ recipients can receive rabies and infect themselves in many countries such as the USA, China, India, France and Germany. It is also proven that the kidneys are the organs that actually accumulate rabies but not directly affected by the infection. The lesion of the kidney comes from the indirect effect of rabies encephalitis itself. As some mechanisms of the body and organs consist of pathogenesis, Immune system dodging by infectious P-protein or latent into the body''''s dendritic cells or processes Glycosylation. Which of these things makes the kidneys not directly damaged by rabies. This could be a guideline or hope in future studies of rabies treatment. And is a case study that must focus on organ transplant cases as well.