University of Tabriz Journal of Zoonotic Diseases 2476-535X 5 1 2021 04 01 A case report of Sarcocystis sp. isolated from a tumor-like tissue mass on the back of a 6-year-old ewe in Isfahan, Iran 44 48 12484 10.22034/jzd.2021.43998.1098 EN Nasser Hajipour Department of Pathobiology, Parasitology Division, Faculty of Veterinary Medicine, University of Tabriz , Tabriz, Iran Medi Salimi Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran Habib Allah Rashidzadeh Graduated of Veterinary Medicine, Faculty of Veterinary Medicine, University of Sharekord, Shahrekord, Iran Ata Kaboudari Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Journal Article 2021 01 13 <strong>Summary</strong><br /> Sarcocystosis is a zoonotic disease in sheep caused by an intracellular parasite belongs to the phylum Apicomplexa, order Eucoccidioria, and Sarcocystidae family. In the parasite life cycle, there is a need for an intermediate host and a definite host. Some species of <em>Sarcocystis</em> can cause disease and consequently cause weight loss, anorexia, fever, anemia, muscle weakness, decreased milk production, abortion, and sometimes death in intermediate hosts such as cattle, goats, and sheep. Cysts of <em>Sarcocystis</em> spp. are found nearly always in skeletal, striated muscles, particularly in the diaphragm, heart, liver, lungs, and esophageal.  A six-years-old native ewe was referred to the veterinary clinic in Najafabad, Isfahan province, Iran with major clinical signs of nasal discharge, enlarged superficial lymph nodes, anorexia, and a round tumor-like mass on the back. After tissue processing and hematoxylin and eosin staining, different sizes of <em>Sarcocystis</em> spp. (with 3.03 ± 0.44 µm in length) each surrounded by a thin layer of muscle fibers and contained banana-shape bradyzoites were seen in the subcutaneous muscle fibers. Hemorrhage and infiltration of inflammatory cells, mainly, neutrophils were also seen in the dermis. https://jzd.tabrizu.ac.ir/article_12484_46f04262ca6c1b659c4415ce935b93be.pdf